I did experience fatigue, but my body adjusted to it over time. Some of us reduce the dose early on (to two rather than eight "clicks" on the pen) and move up slowly to a higher level I ended up with 7/8 dose and had excellent gains). I also found that if I got up and out or even went for a walk or tai chi, it seemed to help the fatigue paradoxically. But everyone is different.

Have you checked your blood pressure? Tymlos can lower it for a few hours. It helps to hydrate and even eat some salty crackers before hand. I had a home blood pressure cuff to check on bp.