@frouke I highly encourage getting genetic testing. I was in the hospital in 2020 and was given an SSRI drug Fluoxetine. It lowered my sodium to 115, I spent three days in ICU. The hospital did a test, RX Match, that showed I cannot take SSRI drugs! It was worth the $250 to get tested. My insurance wouldn’t cover but well worth knowing this info. It also showed I have a gene variant MTHFR C667T Heterozygous which can cause depression and anxiety of which I have both. Due to this variant I have to take L-methylfolate (prescription) indefinitely. I’ve been on Mirtazapine since then and I feel great on it. I’m still struggling a bit with sleeping. The doctor had to adjust the dosage once. It does tend to increase your appetite a little, at least it did with me. It’s taken me six mos to lose 17 lbs!