I had the same problem about a year ago. I started having peripheral neuropathy by my neurologist shortly after getting badly dehydrated. My neurologist did just about every test possible and the only thing that showed up was high vitamin B6 and I was only taking about 25 mg. She told me to stop all B6 immediately. It took a few weeks but I started to get better. About 3 months later I was pretty much back to normal. Apparently many of us (especially those with European ancestry) has a MTHFR gene mutation that causes our body to absorb vitamin B6 (and some other supposedly water soluble vitamins as well) instead of just urinating out the excess. I would suggest stopping not only vitamin B6 supplements but also all fortified foods like cereal and protein powders because many of them contain B6 as well.