I'm also stage 4 in the bones, and have been on Orgovyx (Relugolix) for a few months, and Firmagon (Degarelix) for 2½ years before that. In combination with debulking surgery to the lesion on my spine, radiation to my spine and prostate, and Erleada (Apalutamide), they brought my PSA down rapidly from 67 to < 0.01 (undetectable) and have held it there for coming up on three years.

Everyone's cancer is different, so everyone's experience will be too. I just wanted to let you know that GnRH receptor antagonists (first Degarelix and then Relugolix) have worked well at controlling my own bone metastatic PCa.

Good luck with your decision.

Being in stage 4 and having gone through a substantial clinical trial that worked like nothing had prior, here's my opinion. If, what you have done or are doing hasn't resolved the problem, move on. Cancer doesn't wait for anyone for any reason.