Reclast side effects

Posted by dingus @dingus, Aug 15 2:24pm

Does anyone have a solution to combat Reclast side effects. I had the infusion a year and a half ago and the side effects started shortly after I had the infusion. I still have weak legs, swelling in feet, pain in bones, dizziness (serious dizziness), cold sweats, tired all the time and nervous twitching in bones. Any suggestions?

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

@sessioja

my reply disappeared before I finished but won’t repeat will just say— couldn’t sleep night after Reclast infusion, heart beat at 137,,sweating, miserable, Next afternoon went to ED — heart still in tachycardia , now in AFib
also It was terrifying. Got hydration AV and they did all kinds of tests. Sent me home after afib calmed. PA in endo office says never heard of Reclast causing that

Jump to this post

My doctor and I came to no conclusion. I was sick in a recliner chair for months, actually. My husband cared for me. I hurt all over and experienced what I call electricity running throughout my body. Many times and I asked my husband to sit with me until I fell asleep because I was afraid I was going to die. I won't take it again. Reclast stays in your body for years. On my next DEXA, my bone density improved by .6 points. I went from a -3.9 to a -3.3 . I had the doctor do a test that shows if you're losing bone and I am not. So I'm now I go to the gym, I walk, I weight train, and I eat really well, as well as, take supplements. I have had no fractures. I hinge at the hips when I need or want to reach forward or pick up items on the floor.
There are many sites on u-tube and Facebook that help. I will not do a biophisphinate again. I hope I answered you. If not let me know! Blessings to you.

REPLY
@nitzapitza

Wow!….i also has bad reaction for reclast!…i told my doctor I will not take it again….the reason…..non of them report it. I think we all need to call CDC and report it. I decided to continue of eating healthy, exercising especially weight bearing. I follow BONE COACH. He’s a person that the age of 29 was diagnosed with sever osteoporosis. Good luck

Jump to this post

I did bone coach when I had recuperated from the infusion. I still use most of the principles. I think I do better on my own since the program. I get his ads for the line of supplements he uses. Doctors make $ everytime we take their meds. Have you learned about the "bone" that is laid down after a biophisphinate? This "bone" is like chalk and crumbles. It is dangerous stuff.
I am not going to take it again!

REPLY
@awfultruth

@windyshores It has finally become clear to me that the dosages of the drugs available are not chosen based on what's good for the individual. Instead the dosages reflect economic interests and what "they" think will work best for all women with osteoporosis assuming that treatment will not be individualized and nuanced.
For instance, as long ago as 2002 they did a study showing you get almost identical results with Reclast dosages ranging from 0.25 mg to 4 mg with dosing schedules varied depending on the size of the dose. By dosing 0.25 mg at 3 months they accomplished the same bone benefits as 4 mg at one year. So a total of 1 mg in a year got the same result as 4 mg in one year. But what was desired by the various researchers and experts was it seems to improve compliance and convenience and reduce cost and produce the greatest good for all. Assuming of course that there is no health impact of using 4 times more of a drug than necessary to produce the same effect.
"Women received placebo or intravenous zoledronic
acid in doses of 0.25 mg, 0.5 mg, or 1 mg at three month intervals. In addition, one group received a total annual dose of 4 mg as a single dose, and another
received two doses of 2 mg each, six months apart.
Lumbar-spine bone mineral density was the primary end point. There were similar increases in bone mineral density in all the zoledronic acid groups".
See https://www.nejm.org/doi/pdf/10.1056/NEJMoa011807?download=true
There is a paywall for the New England Journal of Medicine (NEJM) but you can create a free account and get 3 free reads a month. That's how I got this paper.
I there are one or two more papers related to this that I have to finish checking out.
Thanks Windy for all your input on this forum.

Jump to this post

@awfultruth thank you for posting that link and info! I have been looking for it. As you probably know I have done one 1 mg dose of Reclast (and had 5 days of fever). I was going to do 1.5mg in September, 3 months later, because I remembered reading that 0.25 was as effective as 0.5mg but I am going to talk to my doctor about this study. I would love to do 0. mg every 3 months.

I believe doses are determined by studies (and by manufacturing needs in some cases. For instance, Radius probably doesn't want to spend money to make injection pens of varying full doses. They were smart to make it adjustable!) I did one, not two, shots of Evenity, two out of four times, because a study on that also indicated that dosing varied by weight and the study was based on weight much higher than mine. Some of us are small- another factor!

For every other med that I take, I do 1/4 dose and often react if I do more. I am older, 105 lbs., kidneys aren't great, generally sensitive. I feel fortunate that my doctor recognizes this problem. ps the 4mg zoledronic acid is Zometa, Reclast is 5mg!

REPLY
@pacred

I am scheduled for my 1st reclast infusion in September. I am allergic to aspirin which is salicylic acid. I get hives and rashes when I take aspirin. I've read that people with sensitivity to salicylic acid take caution with reclast. Does anyone in the group with allergy to aspirin ever had reclast?

Jump to this post

This question was asked in Dec 2023, you can search in Connect for this topic: "reclast and aspirin allergy". Someone wrote a long answer, here is a portion of it: "on drugs.com in the Reclast Prescribing Information: "While not observed in clinical trials with Reclast, there have been reports of bronchoconstriction in aspirin-sensitive patients receiving bisphosphonates. Use Reclast with caution in aspirin-sensitive patients."

REPLY
@heartfelt70

I did bone coach when I had recuperated from the infusion. I still use most of the principles. I think I do better on my own since the program. I get his ads for the line of supplements he uses. Doctors make $ everytime we take their meds. Have you learned about the "bone" that is laid down after a biophisphinate? This "bone" is like chalk and crumbles. It is dangerous stuff.
I am not going to take it again!

Jump to this post

@heartfelt70 can you cite your statement that bones after bisphosphonates are "like chalk" and "crumble"? It is commonly known that bisphosphonates should not be taken for more than 3-5 years, because bone density is increased by lowering bone turnover, so there is less or no new bone. But the incidence of femur fracture or jaw necrosis in that time frame is rare.

This mechanism for bone growth IS a reason to do an anabolic first!

I am curious how doctors make money when they give us meds. Sincere question. I am sure you are right but I would like to know the mechanism.

I am sorry you had an awful reaction. I have also had awful reactions to many meds. But some do fine with bisphosphonates and benefit. Those people tend not to post here because they have no reason to.

I am cautious and am doing low doses and apart from fever have done okay with it.

REPLY
@ripley

This question was asked in Dec 2023, you can search in Connect for this topic: "reclast and aspirin allergy". Someone wrote a long answer, here is a portion of it: "on drugs.com in the Reclast Prescribing Information: "While not observed in clinical trials with Reclast, there have been reports of bronchoconstriction in aspirin-sensitive patients receiving bisphosphonates. Use Reclast with caution in aspirin-sensitive patients."

Jump to this post

I am going to ask my doctor what "proceed with caution" measures I should take. Maybe benadryl before infusion? I will update re what my doctor will advise and I will also update this group after my first infusion.

REPLY

Thanks to everyone. This is a most amazing thread.

REPLY
@heartfelt70

I did bone coach when I had recuperated from the infusion. I still use most of the principles. I think I do better on my own since the program. I get his ads for the line of supplements he uses. Doctors make $ everytime we take their meds. Have you learned about the "bone" that is laid down after a biophisphinate? This "bone" is like chalk and crumbles. It is dangerous stuff.
I am not going to take it again!

Jump to this post

Thank you for your reply. I do not buy anything from from bone coach, just educate myself. After 3 different osteoporosis injections I learned it's all poison to my body. I'm on my own now and my endocrinologist understands my point. He not agreed/disagreed but will continue evaluateing me with DEXA every 2years and blood test every so often. I found a collagen for joint that makes joints a lot better. I found myself for the first time walking on the beach with no aches and pains....got great reviews..the company's name SPARKLE sold on Amazon. I spoke with the company a few times just to educate and talk about my concern. 3 months into using the product, so far I'm very happy...one thing for sure....I feel better and stronger without the meds. I keep walking, weight bearing, eating right and taking the right supplements. Will see what DEXA results will be in November. Good luck to all of us

REPLY

Did Medicare cover the cost for RECLAST if given more than once a year?

REPLY
@06111945cc

Did Medicare cover the cost for RECLAST if given more than once a year?

Jump to this post

The nurse told me that some people have problems and that I should check. My insurance told me that as long as the doctor ordered it, they will pay. The order is for a year, not for an individual treatment. I have a BC/BS Medicare Advantage PPO plan.

REPLY
Please sign in or register to post a reply.