I was on Amitriptyline low dose for quite awhile, I had actually started on them for nerve pain and it worked great…I was taken off them because I developed rapid heartbeats after having covid, the cardiologist said they were bad and the heart and actually contributed to the problem…I can’t take the newer antidepressants so I started on Mirtazapine about two weeks ago because I can tolerate them since they are in the same class of antidepressants called Tetracyclics. I don’t really feel anything yet and I’m not sleeping any better, I also need some weight gain and it seems that they help with that…I would like to get a dna test to determine what would work best for me with anxiety and depression, my eldest son is trying mushrooms for anxiety and he says it really helps him but I am afraid to try them.. I have done some research on it and it’s rapidly becoming more popular because they don’t have lots of side effects…I would like to hear more about this option from people who have tried it.