@rjlpool502 You are correct to question your doctor's recommendation as to why he feels it might work this time. Taking charge of your medical care is necessary to receive the best of care. Perhaps a second opinion at this point? Adstiladrin was recently approved for bladder cancer that is nonresponsive to BCG and non muscle invasive. I would certainly ask your doctor about it. I don't know the percentages of success/failure, sorry. Good luck to you and remember that a second opinion, especially from a large cancer center or referral hospital is a valuable tool. My husband was unable to try this treatment as it was not approved yet, and now lives with a neobladdder, but so far cancer free.