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Prolia and its side effects.

Osteoporosis & Bone Health | Last Active: Aug 20 10:39pm | Replies (69)

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@neesie0159

I finished Evenity on June 18, and am supposed to start Prolia. Between moving and having to hassle providers, call multiple locations to get sooner appointments for DEXA and for endocrinologist appointment, I am now waiting for prior authorization from insurance for the Prolia, because after over a week since seeing the endocrinologist they still have not submitted it. I have to also find a location covered by my insurance that will give the injections. Had I not moved, my rheumatologist’s office would have had all this taken care of by now. I thought moving to a larger metro area would make getting care easier, but oddly enough wait times are longer for anything. I still wouldn’t have even had my post Evenity DEXA had I not called every imaging provider within miles to get an appointment. Not that I’m looking forward to Prolia, I am actually terrified, but if I am going to do it I just want it over with. Any advice to prepare for it when I finally do get scheduled?

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Replies to "I finished Evenity on June 18, and am supposed to start Prolia. Between moving and having..."

@neesie0159 are you going to discuss with your doctor whether you stay on Prolia or transition to Reclast? As your probably know, Prolia has a rebound if stopped, with bone density going down and fracture risk going up, apparently, according to my doctor, rather dramatically. There has been discussion here about Keith McCormick's advice ("Great Bones" author) that rebound may be less strong if you don't do more than 3 shots of Prolia, and that then you might even be able to d Fosamax vs Reclast. I don't know much about any of this because my docs rarely use Prolia. Just raising the issue that you can explore with your doctor.

Dr. Ben Leder's video "Combining and Sequencing Approaches to Osteoporosis" has some positive info on the potency of Prolia for bone density, but also shares the same concern about rebound and admits he doesn't use it as much anymore. Still, his charts show strong effetiveness if used as a follow-up. We need more research!

sorry you've had to go through so much here.
I hated making the choice of which drug to choose to take after an ankle fracture, and poor dexa results... but I kicked myself into gear and chose prolia 2 years ago.
just had a bone scan and there is significant improvement....but most importantly There have been zero side effects...
Hang in there and Best of luck

I would appreciate knowing if anyone had "delayed" adverse reactions to Reclast. I have had no reaction after one year of use of Reclast.
An attempt was made to place me on Prolia before switching me to Reclast. I had a delayed adverse reaction to Prolia seven weeks later following the injection.
This reaction was the development of hives. So look for bumps on your skin. I was not treated immediately with Presidone while waiting for an evaluation by the Allergist. So, it became worse without the treatment. The prescriber was denying Prolia as the cause. Has anyone developed hives as a severe allergic reaction to these injections or infusions? Thank you.