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Mixed results 1 year after Forteo: What are your thoughts?

Osteoporosis & Bone Health | Last Active: Aug 15, 2024 | Replies (86)
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@windyshores

@loriesco maybe you are having the Trabecular Bone Score-? That measures quality rather then quantity, I have been told.

@gently as always interesting ideas. That "ratio" is the "window" Leder refers to. If osteoclasts are night workers and we test at 8am, maybe that confounds accuracy. Apparently there are other factors, including kidney function. I read once that the BSAP, bone specific alkaline phosphatase is a good substitute but I don't know anything about it. With kidney disease I am going to ask my endo.

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Replies to "@loriesco maybe you are having the Trabecular Bone Score-? That measures quality rather then quantity, I..."
gently | @gently | Aug 13, 2024

CTX and P1NP are excreted through the kidneys elevating the concentration in the blood when kidney function is lower. I read that BSAP is not affected by CKD https://pubmed.ncbi.nlm.nih.gov/28429547/
Yes, the anabolic window, but the window with the cleanest glass, the one that lets the most bone. How many osteoblasts does it take to keep up with one osteoclast. The endocrinologist I see the most often says that it doesn't work that way. The bone pathologist that I only talk to by phone and hardly ever says that is how it works. I never argue.

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