Anyone with CKD & type 2 diabetes taking Farxiga (dapagliflozin)?
My endocrinologist suggested I take Farxiga to help with Type 2 diabetic issues and protect Stage 3B from becoming more serious. She is a great doc and follows the science of this drug. Several months after taking the drug, my outside of Mayo nephrologist back then questioned the validity of the drug. So I went to WebMD online, which is not a truly scientific source for information, say that Stage 3B should not be taking the drug, so I stopped last November without the good wishes of my endocrinologist. Fast forward to past February, I see a New Mayo nephrologist who strongly concurs with the usage of Farxiga with my endocrinologist. Both explain that it is the science that encourages them with CKD. When I stopped taking Farxiga, my GFR was 45 and 44 respectively. I restarted Farxiga around March 1st, and my latest GFR was 37. Granted I have had fluctuations in the past, but unsure of the future GFR direction. I will be tested again next week so I will have a better idea. In the meantime, are there any of you who have taken Farxiga and can share your results as it relates to CKD? I know some have talked a little as it affects heart problems or side effects, but I saw very little on this forum with CKD.
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What would be the herbal medicine?
Hi,
I'm T2 on insulin as I reacted to all known oral diabetes meds. I'm CKD about GFR 40 t0 45 average. What you do prior to being tested can affect the results. I try to be doing the same things when due for testing and generally at the same time of day to keep some consitancy to the results.
Empagliaflozin is the last pill I was prescribed, it is supposed to be good for kidneys while treating diabetes. Sadly for me it kept knocking me out 3 hours after taking, everyday. Although it is not recorded as a side effect. Stop taking it and away went the knock outs. Start it again and back are the knock outs. Did it 3 times to be sure. My GFR remaind stable through out. I guess all the --flozins work similar. Hopefully with out the knock out effect I get.
All medicines have side effects, what matters is can tolerate them or not.
Once you start with multiple health issues, mitigation is the only option left. Most Dr's opt to risk your kidney health at the stage we are, some do it without your consultation. I always question the choices now to be satisfied we are taking the right action.
Cheers
From my experience the side effects of the medications kill the kidneys faster than CKD and IGA nephropathy. For example, prednisone increase calcium in the blood which deadly for both kidneys and heart and many blood pressure medications increase potassium which again bad for kidneys. The truth of the matter is to this day science has not been able to find any medicine that can hit the CKD on the spot and treat it from the root cause. Most medications prescribed by doctors work around and on the suburbs of CKD. After all doctors must also make a living and need to justify their fees with prescribed medicine which as usual comes at the cost of the patient.
I am diabetic (50ish years) and I have CKD stage 4. I have a local endocrinologist and a local nephrologist (part of the same healthcare system) who work with each other and me to develop an individualized / customized treatment plan that suits my needs. I have also been seen by Mayo Clinic providers (for pretransplant evaluation). The Mayo providers have always been willing to give input, collaborate and consult with my local providers for my best interests. It is important for the patient to have a medical team with trust and respect while prioritizing the patient’s needs. At Mayo Clinic Connect we don’t diagnose or prescribe. So in regards to a medication all we can do is share the stories of our experiences with the medication. All medications have side effects. The patient’s responsibility (with input from their team) is to determine what they’re willing to tolerate and what their priorities for treatment are. For example someone may be willing to put up with an unpleasant side effect of a medication if an improvement in a condition is possible. That brings up tests and measurements such as eGFR to assess whether there is any improvement. Many tests must be looked at over a period of time (trend) and are not just a one time snapshot to be useful. eGFR is like that. It is also influenced by other factors (hydration, labs & testing equipment used, other medications and physical conditions …..) It is best to keep everything as consistent as possible when doing these tests.
Whatever medications, treatments and measurements you use to care for your diabetes &/or CKD strive for good communication to work toward the goal of your best health possible.
Hi,
Brilliant post.
In my humble opinion Dr's usually mitigate without keeping their patients informed of why and what they are doing. Once you are under speacialist consultants the full picture can emerge. I think patients should be questioning everything from day one, which is not what we normally do, Dr's know what they are doing, right, you would thinks so. When the penny drops you start fact checking everything and start questioning the choices being made for you.
I have spent 12 years refusing to accept mitigating my kidneys for other health gains. I now take meds that are known to damage kidneys as other health issues have become more important to attend to, but I do so knowing what the consequences will be with the support of my Dr's.
Cheers