@naiviv ,
I haven’t been on the connect.mayoclinic website in a few months, so when I clicked on today the first post I saw was yours. I visited the site today trying to find some insight on the blood test results I got yesterday. I am also on metformin 2x a day after meals. I was in shock by the results of my B12 test, I was not on the low end, but rather almost 3000 points higher than the highest end of the acceptable range. I wish I had a loss of appetite, but the only other side effect for me is severe constipation. Amazing how the same drug can have such opposite effects. Just for reference,
I was diagnosed almost 1 year ago at the age of 67.