Good morning, @paisleyshakell. From my personal experience of having an aggressive form of leukemia with three offending mutations, that didn’t prevent me from having several MRIs with contrast when required. Having ET with the JAK2 mutation, based on my experience with a blood cancer, seems like it shouldn’t have any bearing on the MRI or interfere with your health. Reactions to the contrast material is rare.

Contrast is important with some imaging because it enhances the quality of the images. This improves the sensitivity and specificity of the diagnostic images to give your doctor a better, detailed look at the tear.

What is your main concern? Have you had an MRI before?