I am 62 years old and have suffered from migraines for 20 years. I used to get them 4 days/week and have tried every medication, Botox and other injections currently on the market as well as some non traditional ideas. Rizatriptan (Maxalt) did help a lot in stopping my migraines when they occurred. However, it did not reduce the amount migraines and at times I had rebound headaches. I now get Vyepti infusions quarterly and only experience one migraine/month. I still use the Rizatriptan as a rescue drug when I do have a migraine. This has been life changing for me.

I’ve been doing these infusions for a couple of tears. at first I had some relief. Now, perhaps some lessening of the severity but no help with frequency if migraines. My doctor and I agreed this past week to stop the infusions.

@susanfalcon52 I have had 3 (300 mg max amount) infusions. For the past 2 years I have had up to 22 migraine days per month. 2 years ago I had a Thunderclap headache and I was in the hospital for 8 days because they could not get it stopped. After that my headaches turned into status migrainosus. It was miserable, nothing seemed to work. My Neurologist put me on Botox and Vyepti. The first month I did not have a headache for 2 months! Then month 3 they started back. The 2nd infusion seemed to not help at all. Before my 3rd infusion, I changed my diet. I eat between Mediterranean and Low Carb. I am a SWEETaholic. I do not eat any of the crazy ingredients that you can't pronounce in any of my foods now. So on my 3rd infusion, 2 weeks ago, the first week was great. Then I had 3 bad days and this past week has been much better. So I think a combination of the 3 is so far helping me. The only side effect from Vyepti that I have had was a stuffy nose. To me, I had to at least try Yvepti since nothing else was working and it has helped.