1. < Prostate Cancer

Ivermectin for Prostate Cancer? (Being studied)

Posted by tvz @tvz, Apr 7 4:56pm

I am 54 and have Gleason 3+4 in 8% of one lobe. My PSA rose from 8.1 to 9.6 in the past 6 months. I’ve heard Ivermectin has potential to slow growth of cancer cells. Has anyone tried IVM or any other medication that has been shown to slow growth?

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chamblee54 | @chamblee54 | Aug 8 3:09pm
In reply to @northoftheborder "" They have stage 4 and as they put it , what do I have to..." + (show)
@northoftheborder

" They have stage 4 and as they put it , what do I have to lose !?"

Please. I have stage 4 cancer, and I believe I have a *lot* to lose. That's why I'm taking genuinely researched and approved treatments, which have done a great job keeping me alive and healthy over the past three years, and I expect will continue to do so for many years to come. We are fortune to have so many excellent treatment options now.

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My poor choice of words. My apologies. What I meant was they felt like taking Ivermectin was the right choice and risk for them given their diagnosis.

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heavyphil | @heavyphil | Aug 8 3:42pm
In reply to @northoftheborder "" They have stage 4 and as they put it , what do I have to..." + (show)
@northoftheborder

" They have stage 4 and as they put it , what do I have to lose !?"

Please. I have stage 4 cancer, and I believe I have a *lot* to lose. That's why I'm taking genuinely researched and approved treatments, which have done a great job keeping me alive and healthy over the past three years, and I expect will continue to do so for many years to come. We are fortune to have so many excellent treatment options now.

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There is a clinical study going on right now in Glasgow using docetaxel and mebendazole ( similar to ivermectin) which disrupts the cellular scaffolding matrix of PCa; the cells die without it.
The study was initiated in 2019 and a result was expected in 3-4 yrs. Factor in Covid and that set it back a bit.
If you search “mebendazole for prostate cancer” you’ll find it. Definitely not mainstream and it wouldn’t be MY first choice at this stage, but down the road this could be a game changer….gotta stay in the game and keep breathing to reap the rewards of all this exciting high tech research.

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2 replies
northoftheborder | @northoftheborder | Aug 8 4:37pm
In reply to @heavyphil "There is a clinical study going on right now in Glasgow using docetaxel and mebendazole (..." + (show)
@heavyphil

There is a clinical study going on right now in Glasgow using docetaxel and mebendazole ( similar to ivermectin) which disrupts the cellular scaffolding matrix of PCa; the cells die without it.
The study was initiated in 2019 and a result was expected in 3-4 yrs. Factor in Covid and that set it back a bit.
If you search “mebendazole for prostate cancer” you’ll find it. Definitely not mainstream and it wouldn’t be MY first choice at this stage, but down the road this could be a game changer….gotta stay in the game and keep breathing to reap the rewards of all this exciting high tech research.

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Yes, I agree. There's a lot of very exciting stuff in the pipeline. Most of it won't end up panning out (see @kujhawk1978 's excellent summary of research stages a few posts earlier), but that's OK. We don't need them all to succeed; even if most fail, one or two successes could be enough to tip the balance for us.

(I wish I did know which 2 or 3 of the dozens of "promising" PCa treatments in early research will make it, because then I could take all of our family's savings and invest them in the company that's doing them. Even if I didn't live long enough to make millions, it would be a nice nest egg for my family. 😉 ).

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1 reply
Moderator
Colleen Young, Connect Director | @colleenyoung | Aug 8 5:21pm
In reply to @heavyphil "There is a clinical study going on right now in Glasgow using docetaxel and mebendazole (..." + (show)
@heavyphil

There is a clinical study going on right now in Glasgow using docetaxel and mebendazole ( similar to ivermectin) which disrupts the cellular scaffolding matrix of PCa; the cells die without it.
The study was initiated in 2019 and a result was expected in 3-4 yrs. Factor in Covid and that set it back a bit.
If you search “mebendazole for prostate cancer” you’ll find it. Definitely not mainstream and it wouldn’t be MY first choice at this stage, but down the road this could be a game changer….gotta stay in the game and keep breathing to reap the rewards of all this exciting high tech research.

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@heavyphil, here's an article describing the research you mention
- A bold new treatment for prostate cancer could soon be available by repurposing an existing drug. https://www.gla.ac.uk/research/beacons/precisionmedicine/researchfeatures/cancerresearch/prostatecancerresearch/

It is important to note that this promising article describes research in pre-clinical trials, meaning, in mice and not yet in human trials. See @kujhawk1978's post describing research phases https://connect.mayoclinic.org/comment/1119887/

Repurposing existing drugs for cancer treatments is a focus of some research trials for good reason. As the Glasgow article states "Drug repurposing in this way is advantageous as existing drugs already have satisfactory safety records. They can therefore be fast-tracked to treat the new disease."

An exciting research area to follow for the hoepfully not so distant future. Not sure what researchers consider "soon". It might differ from a patient's definition of soon. 😕

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2 replies
northoftheborder | @northoftheborder | Aug 8 7:19pm
In reply to @colleenyoung "@heavyphil, here's an article describing the research you mention - A bold new treatment for prostate..." + (show)
@colleenyoung

@heavyphil, here's an article describing the research you mention
- A bold new treatment for prostate cancer could soon be available by repurposing an existing drug. https://www.gla.ac.uk/research/beacons/precisionmedicine/researchfeatures/cancerresearch/prostatecancerresearch/

It is important to note that this promising article describes research in pre-clinical trials, meaning, in mice and not yet in human trials. See @kujhawk1978's post describing research phases https://connect.mayoclinic.org/comment/1119887/

Repurposing existing drugs for cancer treatments is a focus of some research trials for good reason. As the Glasgow article states "Drug repurposing in this way is advantageous as existing drugs already have satisfactory safety records. They can therefore be fast-tracked to treat the new disease."

An exciting research area to follow for the hoepfully not so distant future. Not sure what researchers consider "soon". It might differ from a patient's definition of soon. 😕

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Thanks! It's very heartening to see so much research going on, both with new treatments and repurposing existing ones.

Even if it does end up in clinical use for PCa "soon" (however we define that), it's important for all of us to remember that we don't know the right dose, strength, or formulation yet. Taking it wrong might do nothing, might produce dangerous side-effects, or might even make the cancer worse. 🙁

It's hard to be patient when it feels like time is our enemy, but the latest treatments for metastatic PCa are buying us more of it.

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heavyphil | @heavyphil | Aug 8 8:09pm
In reply to @colleenyoung "@heavyphil, here's an article describing the research you mention - A bold new treatment for prostate..." + (show)
@colleenyoung

@heavyphil, here's an article describing the research you mention
- A bold new treatment for prostate cancer could soon be available by repurposing an existing drug. https://www.gla.ac.uk/research/beacons/precisionmedicine/researchfeatures/cancerresearch/prostatecancerresearch/

It is important to note that this promising article describes research in pre-clinical trials, meaning, in mice and not yet in human trials. See @kujhawk1978's post describing research phases https://connect.mayoclinic.org/comment/1119887/

Repurposing existing drugs for cancer treatments is a focus of some research trials for good reason. As the Glasgow article states "Drug repurposing in this way is advantageous as existing drugs already have satisfactory safety records. They can therefore be fast-tracked to treat the new disease."

An exciting research area to follow for the hoepfully not so distant future. Not sure what researchers consider "soon". It might differ from a patient's definition of soon. 😕

Jump to this post

Yes, Colleen, that was the article - thanks for the URL - I can never get that right!

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heavyphil | @heavyphil | Aug 8 8:12pm
In reply to @northoftheborder "Yes, I agree. There's a lot of very exciting stuff in the pipeline. Most of it..." + (show)
@northoftheborder

Yes, I agree. There's a lot of very exciting stuff in the pipeline. Most of it won't end up panning out (see @kujhawk1978 's excellent summary of research stages a few posts earlier), but that's OK. We don't need them all to succeed; even if most fail, one or two successes could be enough to tip the balance for us.

(I wish I did know which 2 or 3 of the dozens of "promising" PCa treatments in early research will make it, because then I could take all of our family's savings and invest them in the company that's doing them. Even if I didn't live long enough to make millions, it would be a nice nest egg for my family. 😉 ).

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Now THAT is what’s called “making lemonade outta lemons”!😂

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kujhawk1978 | @kujhawk1978 | Aug 9 9:04am
In reply to @chamblee54 "I have a friend who was recently diagnosed with cancer. They are taking Ivermectin. They have..." + (show)
@chamblee54

I have a friend who was recently diagnosed with cancer. They are taking Ivermectin. They have stage 4 and as they put it , what do I have to lose !? Use the tools that are available. Let’s face it, big Pharma isn’t going to promote it.
Many Functional Drs are using it.

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....Functional medicine doctors use a more holistic approach to treat chronic conditions. This includes taking your lifestyle, genetics, mental health, and environment into account when making a treatment plan.

Hmm, Stage 4 cancers may not necessarily be chronic condition. They may be the opposite, fatal.

"Use the tools that are available", exactly, those which have credible medical research to support their use.

Any source to go along with that statement "Many functional doctors are using it..!?"

Really, Big Pharma, exactly what do your mean by that. I think we all generally agree the US health system which includes pharmaceuticals has room for improvement - insurance, for profit hospitals...(I just finished interacting with an ER and Cardiology on an issue with my wife over the last month, they identified the problem, prescribed treatment, resolved it. There were things they could have done better and I let them know). Still, the plethora of choices we have, the ARIs, Orgovyx, Lutetium and others...may have increased longevity for many.

Kevin

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jjensen155 | @jjensen155 | Aug 9 2:18pm
In reply to @chamblee54 "I have a friend who was recently diagnosed with cancer. They are taking Ivermectin. They have..." + (show)
@chamblee54

I have a friend who was recently diagnosed with cancer. They are taking Ivermectin. They have stage 4 and as they put it , what do I have to lose !? Use the tools that are available. Let’s face it, big Pharma isn’t going to promote it.
Many Functional Drs are using it.

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@chamblee54 -- by chance do you have any of the Functional Drs. names using Ivermectin? I am interested from an educational point of view.

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VancouverIslandHiker | @vancouverislandhiker | Aug 10 11:31am

Yes, there are plenty of studies right now with Ivermectin and its derivatives and Protate Cancer. One of my friends started taking 'Menben' ( Spelling? ..or some derivative like this) and has had great success on it . His PSA went way down from about 2.0 to 0.056 . He did a 3 week cycle he said with zero side effects . I cant say what the strength was or MG he took . But from his stand point - it worked on him . There is massive hope in this group of drugs .

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