I am hesitant to reply here, as my medical knowledge is extremely small. I'm in a clinical trial at the NIH for Olaparib use on pancreatic acinar cell carcinoma. PACC is very rare and I learned from talking to the doctors at the NIH that Olaparib is not useful unless a person has the BRCA 2 mutation in their DNA. It has produced some positive results in my liver tumor since I've been on it according to CT scans. I do have the BRCA 2 mutation. I hope this helps in some way and please do some research on the internet to verify what I've written here. And I'm hoping you can find a 2nd opinion from another oncologist.