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Stopping Myeloma at the MGUS Stage

Blood Cancers & Disorders | Last Active: Sep 14 1:28pm | Replies (27)

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@amyboylan1

Hi,
I was diagnosed with MGUS about six weeks ago. Like all of us I want to do whatever I can to keep it from progressing. I seem to get mixed information about whether there is medication that can lessen the progression or not. Can I please get some information from you who have had it longer. Also, can you tell me where you get the Curcumin? I have only seen Tumeric with Curcumin. I am quite confused about the difference since I’ve seen them in pill form together. I’m so glad I found this group. This new diagnosis is very scary for me and I can use all the support and guidance i can get. I thank you all.

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Replies to "Hi, I was diagnosed with MGUS about six weeks ago. Like all of us I want..."

MGUS is scary, but only a tiny percentage of people have it progress to smoldering MM or MM. It is asymptomatic, so no need for any meds unless it morphs into MM. I mostly just eat healthy, exercise, get enough sleep, and try to manage stress. Tumeric is a root that is related to ginger, and small amounts of an active anti-inflammatory chemical in it is named curcumin. These are poorly absorbed by the GI tract unless one adds black pepper (active ingredient piperine) or takes supplements in which the curcumin has been modified by adding a lipid (fat) molecule to it, which greatly improves absorption. I take a couple of grams of bioavailable (modified) curcumin a day, just to see IF is has any effect on my bloodwork. The brand I use is Qunol, but there are other brands. Unfortunately supplements aren't regulated by the FDA so tis a guess at what works. Check with a doctor before taking supplements because they have side effects. There are a lot of peer-reviewed papers online about MGUS, and ResearchGate also has research. Here are a couple of links: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301229/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111629/