In some respects, I think the questions to be asked would be based on whatever information you already have from the scan that ascertained that she has a meningioma. For example, if you were told that the meningioma is more than 3 centimeters it is unlikely that she would be a candidate for radiation. Then, my first question would be how easily accessible is the location for surgical removal. You could also ask if it would be reasonable to take a watch-and-wait approach and have a repeat scan in 6 months. That is what I did. I needed the time to educate myself and get used to the whole idea of having a craniotomy. Given that you are going to the Mayo Clinic, you are in good hands and the doctors there will guide you along the way. For what it's worth, I'll offer one bit of advice I was told by my neurosurgeon at U.C.S.F., and that would be, if the patient is healthy, and the meningioma is in a location that is operable, surgical resection is always the first choice.