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@lila1

Diagnosed May 2024. Got 3 opinions, read research. Splenectomy has pros/cons, as does rituximab. They all seem to result in similar OS and PFS. In my estimation it appears a toss up, a personal choice. Would you prefer to have infusions that affect your immune system one way or surgery that affects your immune system another way? Clearly oncologists tout rituxan over OG surgery. But if you are on the young side with low marrow involvement, why would you choose rituxan over surgery? Please freely share advice!

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Replies to "Diagnosed May 2024. Got 3 opinions, read research. Splenectomy has pros/cons, as does rituximab. They all..."

Given that you’ve done your research on both splenectomy vs Rituximab and have gotten 3 opinions…and you, as well as your doctor, are comfortable with your decision to go ahead with the spleen removal then I think you’ve made the decision that’s best for you.
I did find a site you might find helpful in validating your decision: https://www.mayoclinicproceedings.org/article/S0025-6196(19)30506-3/abstract#:~:text=Consensus%20guidelines%20and%20recent%20appraisal%20of%20the%20evidence,treatments%20in%20the%20absence%20of%20increased%20surgery-related%20risks.

I was just going to link you to another member, @bmisslich who had a splenectomy but I see you beat me to it!! ☺️. Hopefully they can give you some insights as to living without a spleen.

Wishing you all the best. Keep me posted, ok?