Unfortunately yes. I had a double mastectomy in 2012 after having chemo. Was put on Tamoxifen 7.5 years. After I reached menopause my Oncologist switched me to Anastrozole and was on it for 6 months. I had back pain, discovered a painful lump in my clavicle shoulder area. PET scan later discovered breast cancer was found in my sternum, liver, bones, spine, abdomen and lymph nodes. A liver biopsy confirmed stage 4 ER+ Her2+ breast cancer had returned and spread in 2022. Did 6 Taxotere, Herceptin & Perjeta chemo infusions in 2022. Had slight progression and was switched to Enhertu Feb 2023. Completed 7 infusions but heart function declined and Enhertu was stopped. Scans showed stable from late 2023 and as recent as Feb 2024. I had a seizure in March 2024 and MRI showed I now have Mets to the brain and will be doing radiation to the brain next week.