My current kappa is 283 and kappa/lambda is 19.3; they have been ramping up from 29 and 2.3 for the last 5 years. My BMB 8 years ago was for baseline, and just showed early stage deranged cells. A scientific paper I read called them deranged, rather than precancerous, a somewhat softer term. My oncologist indicated another BMB once the ratio hits around 60; I see him Friday, so we shall see.