I had to get a bone marrow biopsy to stage my Hodgkin’s Lymphoma. I’m not a very religious person but this wonderful, calming nurse asked if we could pray together and it helped so much as I was just finding out I had cancer and was terrified.Like katgob said, I put my head on a pillow lowered my pants, I was standing up, and they began the numbing portion. When they started to go deep to get into the bone it was very uncomfortable and felt like someone was pounding with a hammer not painful just pressure. Definitely worth getting answers.