What was your highest PSA and still have a clear PET/CT scan?
I just got the results from my most recent PET/CT scan;
"There is no abnormal PSMA uptake to indicate recurrence or metastatic disease anywhere despite the rising PSA."
12/11/2023 PSA 0.02
1/5/2024 PSA 0.08
3/11/2024 PSA 1.02
6/10/2024 PSA 6.67 (This assay was performed using Beckman Coulter reagents and test kits) I'm not sure what that is???
Background; RRP 3/25/2021, 34 rounds Salvage radiation fall 2021
11/11/2023 PSA 6.56 PET/CT showed metastatic lymph node in chest
3/14/2023 began 6 month MetaCure Trial Orgovyx, Erleada and radiation to the lymph node. PSA was < 0.01 at 6 month point when the drugs were stopped 12 weeks later 12/11/2023 PSA was 0.02.
I am on active surveillance, no current treatment. PSA has continued to go up. My last 12 week PSA test was a 5.55 increase.
I have an appointment with one of my Oncologists next week.
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I have a key interest in this topic also and had a discussion with my MAYO uroligist last week. He said the key for him is doubling time. Less than one year and he will get agressive with treatment. Additionally, Dr. Stolz from the PCRI, states in one of his video that 10% of men have prostate cancers that are not detectable on PSMA PET scans. You would find his YouTube video very helpful!
Good luck!
Oncologists are gonna be puzzled as I am.
If I read your numbers correctly, you have just a single test showing a sudden rise in 2024. The first thing I'd do is ask is to repeat it, making sure you don't do anything that might irritate the prostate (like riding a bike or a horse, certain sexual activities, etc) for a few days ahead of the test.
Actually there have been four consecutive rises this year. After two consecutive rises I was withdrawn from the Metacure trial. The last PSA increase was a 5.5 increase in twelve weeks. And your suggestion on a repeat PSA test is spot on. I have already requested another test before I meet with the Oncologist next week.
Thank you for your comment and the link to Dr. Stolz's video. I will check it out.
After I had my prostate removed my PSA was never lower than .37. After that I had 7 weeks of salvage radiation and my PSA nearly doubled during that 7 weeks. Then I got an Oncologist that specialized in Prostate Cancer. When he saw the PSA numbers and the number of consecutive increases me said that he would have expected multiple metastases but my PET/CT scan was clear. Nothing showed until my PSA was 6.56, and then there was just a single metastasis in a lymph node in my chest.
More info for ya: check out the Mayo Clinic Quadra Pet/Ct scanner- only one in North America- it can see the whole body at once. Sorta like the old Hubble Space telescope compared to the new James Webb Space Telescope. Finds cancer quicker, easier to view too… etc.
None of those things matter as Robert had a Prostectomy in 2021. His increases in PSA have been more than doubling in short intervals. He needs to see a Radiation Oncologist ASAP!
Robert, the link I provided earlier to Dr. Scholz was ok, but not what I intended. This link is a video pertinent to you specific situation.
Thanks again for sharing the link/links.