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MGUS FLC Ratio decreasing: Concerned
Blood Cancers & Disorders | Last Active: Jan 12, 2024 | Replies (13)Comment receiving replies
Your ratio going down is good, because your light chains are dominated by Kappa, not lambda. A K/L ratio going down if you are lambda dominant means the lambda chain is going up which is not good news. So I am considered abnormal ratio by that. I really like your encouragement, thank you for your advice! I am yet to meet my physician on Monday so I will know more there! She says I am stable but keeps an eye on these numbers.
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Hi:
I’m lambda dominant too. My K/L ratio fluctuates between 0.46-0.36.
And another oddity is I have as many as 4 monoclonal peaks- all tiny, unquantifiable, and often seem to “disappear”.
My SPEP has shown 2 “IgM lambda, IgG kappa & IgG lambda”. Only the IgG lambda was identified this last May.
So the docs are scratching their heads but aren’t really concerned I will progress. We are all so unique and difficult to compare our labs.
Patty has excellent advice.
Try not to get caught up in the “what ifs”. Ask all your questions Monday and then enjoy life.