Replies to Your ratio going down is good, because your light chains are dominated by Kappa, not lambda….

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Blood Cancers & Disorders | Last Active: Jul 15 11:02pm | Replies (8)

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@hpatel334

Your ratio going down is good, because your light chains are dominated by Kappa, not lambda. A K/L ratio going down if you are lambda dominant means the lambda chain is going up which is not good news. So I am considered abnormal ratio by that. I really like your encouragement, thank you for your advice! I am yet to meet my physician on Monday so I will know more there! She says I am stable but keeps an eye on these numbers.

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Replies to "Your ratio going down is good, because your light chains are dominated by Kappa, not lambda...."

2121 | @leslie2121 | Jul 13 9:59am

Hi:
I’m lambda dominant too. My K/L ratio fluctuates between 0.46-0.36.
And another oddity is I have as many as 4 monoclonal peaks- all tiny, unquantifiable, and often seem to “disappear”.
My SPEP has shown 2 “IgM lambda, IgG kappa & IgG lambda”. Only the IgG lambda was identified this last May.
So the docs are scratching their heads but aren’t really concerned I will progress. We are all so unique and difficult to compare our labs.
Patty has excellent advice.
Try not to get caught up in the “what ifs”. Ask all your questions Monday and then enjoy life.

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