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MGUS FLC Ratio concern

Blood Cancers & Disorders | Last Active: Jul 15 11:02pm | Replies (8)

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@pmm

@hpatel334
Amazing!
I'm not an expert, but a patient but I believe that my hem/onc doc would be pleased by declining numbers and especially the ratio. Mine were steadily increasing but my last bloodwork showed regression to the lower numbers almost identical to my initial blood work when I was diagnosed three years ago. He didn’t dance, but he did crack a smile which for him is a rare gift.
I find it comforting that progression to multiple myeloma is such a low risk. Beyond that, the advances in treatment over the past decade are remarkable.
The mind/body connection is something that is within my means to control. You are doing all the right stuff with exercise, diet and diligence. Finding that balance that allows us to live life fully and enjoy each day was for me, the next step. My physical self responds when my head is in a good place.
Having said all that, when one gets results that are inconsistent with expectations you do need to ask all the questions. Can you ask your physician to speculate or explain this change? I would be really curious to know as well if you feel comfortable letting me know.

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Replies to "@hpatel334 Amazing! I'm not an expert, but a patient but I believe that my hem/onc doc..."

Your ratio going down is good, because your light chains are dominated by Kappa, not lambda. A K/L ratio going down if you are lambda dominant means the lambda chain is going up which is not good news. So I am considered abnormal ratio by that. I really like your encouragement, thank you for your advice! I am yet to meet my physician on Monday so I will know more there! She says I am stable but keeps an eye on these numbers.