Interesting! Iḿ greatly hoping that indeed, that GI upset post-massage was a confirmatory Herxheimer reaction. And perhaps the input of that natto/serra combination, on board for the preceding 3 weeks, helped to make that massage even more effective than it might otherwise have been. I do like the idea of multiple healing therapies producing exponential benefits. I expect to stay on serrapeptase indefinitely if it produces the breakthrough that I sometimes feel is beginning, but long-term use of these proteolytic enzymes, like high dosing of these enzymes, has not yet been carefully studied. . .Needless to say, this does not deter me, at the moment. The topical (intransal spray) drugs I was pressured to stay on in the early days of my long COVID definitely did some damage from which I am still trying to recover, and yet the medical literature is LOADED with ¨proofs¨ that using those drugs forever is perfectly safe for everyone. Ugh . . .