Peripheral Neuropathy: bad reaction to pain and antibiotic meds

Posted by lgpn5094 @lgpn5094, Mar 10 8:14pm

Have small fiber idiopathic PN. I take Gabapantin 600mg per day. I Went to dentist and had two terrible reactions to medication: 1) 800mg ibuprofen OK for 3 days, then trouble walking, then unable to walk or get off the floor. 2) Antibiotic Clindamycin OK for several days, then very sharp pain in one calf and I could NOT walk without a cane due to pain. Anyone experienced hyper reaction to these kinds of drugs?

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@lgpn5094

I now check all safety precautions, google, neurologist, internist.
KEEP in MIND - Always Check for medication complications when used with Gabapentin, including antibiotics and pain medications. We have learned some the hard way.

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I have been taking Gabapentin for 8 years and never thought about it being a problem.My Dr. refuses to refill my Meloxicam.He says its really bad.I had been taking it for 8 years also.I guess i better do some more checking on my drugs.

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Also NOTE: this includes drugs we took SAFELY BEFORE starting GabaPentin.

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Cymbalta,doxycycline, and 2 more that i can't think of right now messed me up from my talking and walking so bad.I did call prescribing dr's and told them how it was acting and they said to quit.

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After reading your post, I realize the peripheral neuropathy that used to be just slightly cold feet got very bad over the last six months and seems to be quickly progressing. Six months ago, I had three bad UTI infections, which is not common for me at all, and had to take several bouts of Cipro and Macrobid. I am now wondering if those antibiotics played any part in what I’m now experiencing?? Seems far-fetched but kind of sounds like what you experienced from a bout with antibiotics.

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@carolinlv

After reading your post, I realize the peripheral neuropathy that used to be just slightly cold feet got very bad over the last six months and seems to be quickly progressing. Six months ago, I had three bad UTI infections, which is not common for me at all, and had to take several bouts of Cipro and Macrobid. I am now wondering if those antibiotics played any part in what I’m now experiencing?? Seems far-fetched but kind of sounds like what you experienced from a bout with antibiotics.

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Very reasonable question, imo. I had severe reaction after one dose of an antibiotic last year. I’m still not sure if it’s the culprit. There’s a theory out there called being floxed. I have no idea of its validity. You can check it out for yourself. I forgot to mention it to my neurologist yesterday. For now, we are working on my B12 deficiency.

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@celia16

Very reasonable question, imo. I had severe reaction after one dose of an antibiotic last year. I’m still not sure if it’s the culprit. There’s a theory out there called being floxed. I have no idea of its validity. You can check it out for yourself. I forgot to mention it to my neurologist yesterday. For now, we are working on my B12 deficiency.

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What are you doing for your B12 deficiency? My youngest daughter recently suggested that may be a problem for me with the symptoms I have.

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@carolinlv

What are you doing for your B12 deficiency? My youngest daughter recently suggested that may be a problem for me with the symptoms I have.

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I’ve read that it’s best to get tested before you take anything for it. My neurologist said he looked at the first number before I started shots. It was found deficient last year and I started daily injections. Then went to daily oral, but the problem is that it wasn’t enough and I needed long term mega sublingual doses. So, by this summer I was still deficient. The neurologist started me on 1000 mcg per day for the indefinite future. For some reason, I don’t process it well. My neurologist says it’s quite common. It’s sad a simple test could avert such terrible damage to the body. I hope yours turns out ok.

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I am on Oxcarbazapine for trigeminal neuralgia. I researched B12 and this medicine and people taking oxcarbazapine had lower or extremely low B12. You can research the meds you are on to see how they interact. If I take my daily Prilosec to close to taking Oxcarbazapine it lessens the effectiveness of both drugs. I research on the National Library of Medicine website.

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@celia16

I’ve read that it’s best to get tested before you take anything for it. My neurologist said he looked at the first number before I started shots. It was found deficient last year and I started daily injections. Then went to daily oral, but the problem is that it wasn’t enough and I needed long term mega sublingual doses. So, by this summer I was still deficient. The neurologist started me on 1000 mcg per day for the indefinite future. For some reason, I don’t process it well. My neurologist says it’s quite common. It’s sad a simple test could avert such terrible damage to the body. I hope yours turns out ok.

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Thank you so much for taking the time to help! You have gone through a lot for a vitamin most don’t ever think could be a problem! Really hoping to get a manageable answer!! I hope you are doing better!

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@carolinlv

Thank you so much for taking the time to help! You have gone through a lot for a vitamin most don’t ever think could be a problem! Really hoping to get a manageable answer!! I hope you are doing better!

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I do think I’m improving. My neurologist says it’ll be very slow, but I have patience. I just pray it eventually turns around. Best of luck to you as well,

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