I’m not a pharmacist or EP, so my answer is only from my own experience with calcium channel and beta blockers.

Having said that, for me personally, neither metoprolol or Losartan did anything to prevent me from going into full blown afib or atrial flutter. What finally helped is a dedicated anti arrhythmic.

The one I am currently on is also used as “pill in the pocket,” and when prescribed in that manner, you take it only when you feel yourself go into tachycardia or afib. However, many people don’t even feel their out of rhythm heart until other more serious symptoms occur—dizziness, exhaustion, nausea, sweating, etc. And with my individual case, it was decided between my EP and I to take Flecainide daily.

It was a good decision as far as I’m concerned. But I still worry about the medication not doing its job well enough after a while. I’ve already had to have a dosage increase as it quit managing things on the lowest dose. I started in February after my last ER visit with Afib where they performed electrocardioversion. (And that didn’t work either.)

As one very kind ER nurse told me, Afib is hard to get a grip on.

The way I look at it now is these drugs are all going to affect each one of our genetic makeups differently. And unfortunately, experimentation on dosing and types are all we can do at this point if ablation hasn’t worked or you are not a candidate for surgical intervention.