What is the recommended treatment after 6 Pluvicto doses?

Posted by donalan @donalan, Mar 13, 2023

I will have had 6 Pluvicto doses next month. PSA has decreased some. SE have been much easier to tolerate than chemotherapy. What is the recommended maintenance treatment after receiving Pluvicto?

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@digger

How was side effects I have pluvicto in my future thanks

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I just finished my 2nd round of Pluvicto, I am feeling very fatigue, lower back pain, exhausted, shortness of breath, almost non functioning, non stop urination, and confused at times otherwise everything is ok.

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@lisab2

@digger My husband's first treatment with Pluvicto was last week. Upon advice of the medical team, we used three days not sleeping in same bed or close contact and 7 days for no contact with children. Another tip -- RNs with the nuclear medicine team administering the treatment emphasized the importance of taking anti-nausea meds immediately after treatment to prevent symptoms (nausea, vomiting). He did that. His only side effect has been fatigue. Good luck on your treatment!

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First round for me was exactly the same. This second round has been a lot tougher.

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After a significant delay - 4 months- I will resume Pluvicto, with careful monitoring of side effects and PSA. Can find no related data.

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@digger

Hi I’m getting my first pluvicto treatment tomorrow any advice,how long did you have to stay away from people 2 days or 3 thanks Dave

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Hello Dave,

I have had 5 Pluvicto treatments so far. Number six coming up in a few weeks.

I bought a dosimeter so I could check on my actual radiation reading instead of just blindly following the official guidelines of staying three feet away from people for three days.

Based on my actual radiation reading history, my personal protocol is to isolate myself completely for one week, i.e. no physical contact, no sleeping with the wife; then for the second week allow brief physical contact - a hug or a handshake ok but no prolonged contact such as cuddling or sleeping together. After two weeks my radiation level is back to "normal" and full contact and sleeping together is ok.

If you are a person like me who wants direct knowledge and wants to make your own decisions concerning your own health, treatments, and how much radiation exposure to your loved ones and caregivers that you personally are ok with, I urge you to do what I did - purchase a dosimeter (about $100 on a Amazon), take daily readings (one at arms length and one touching your body) a come to your own decisions.

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@digger

Hi I’m getting my first pluvicto treatment tomorrow any advice,how long did you have to stay away from people 2 days or 3 thanks Dave

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Russ is on his 3 rd this week at the Mayo Clinic in Rochester Mn ! He does quite well after ! Dr Childs and his team are awesome! They all tell us that u are fine being together just no intimate or kissing for 3 days ! If you have bladder issues he would wear a depend ! He doesn’t have that issue !🙏😊 best of luck on this fight

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On radium 223 or Xofigio 6th shot USA at Peace bridge customs picked me out at car booth and sent me over to office where a gigger counter was aimed at me and results sent to scientist in NYC to attest I had medical Radium 223 only Carry your cards folks

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@rxharleydude

I am currently on Xofigo. Getting ready to get my fourth dose out of six. Won’t really know how effective it is until after the sixth dose and a PMSA scan. Unlike Pluvicto, you don’t have to have had chemo to get Xofigo, so for me Pluvicto would be a potential next step in treatment. But, I would have to have tried a round of chemo first. Most, if not all of my cancer is in the bones and Xofigo focuses only on bone cancer. Pluvicto, on the other hand is reputed to be affective on cancer in the organs and lymph nodes as well.
I really appreciate reading about the experiences and comments of everyone in this group and would like to put a plug in to everyone to include frequent prayer to our God in heaven, giving him thanks for all the good things that happen and asking for his help to cope with the problems.
May God bless and heal us all!

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Did 6 injection Xofigo feel great diarrhea some days getting CT as we speak tomorrow bone scan

Precious blood of Jesus heal me daily

What is next psa 31.4

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@larke

After a significant delay - 4 months- I will resume Pluvicto, with careful monitoring of side effects and PSA. Can find no related data.

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@larke, what led to your having to delay treatment with Pluvicto? How are you doing?

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@colleenyoung

@larke, what led to your having to delay treatment with Pluvicto? How are you doing?

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No initial delay. Completed the usual 6 treatments, six weeks apart. Relative success: PSA 75 to 8. March 13 completed.
Agreed to be a test case for MORE Pluvicto and will likely begin in early August. Likely two or three applications.
Larke

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@larke

No initial delay. Completed the usual 6 treatments, six weeks apart. Relative success: PSA 75 to 8. March 13 completed.
Agreed to be a test case for MORE Pluvicto and will likely begin in early August. Likely two or three applications.
Larke

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larke, I am happy to hear that there are clinical trials for men who could benefit for more than six Pluvicto infusions. My husband is already worrying about what comes after his sixth infusion in August.

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