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Anastrozole - should I take?

Breast Cancer | Last Active: Jul 7 9:19pm | Replies (31)

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@ladyofthelake1

Negative genetic also for me.
Mine is IDC too
We are so very similar types.

They did MammaPrint for me.

Did your surgeon recommend taking out your ovaries? Did he even mention that?

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Replies to "Negative genetic also for me. Mine is IDC too We are so very similar types. They..."

@Janwe W. I have heard of people with positive BRCA gene having both breasts and ovaries removed. For BRCA negative I have not heard of anyone having ovaries out, unless they are premenopausal and want to take an aromatase inhibitor, but ovaries can be suppressed rather than removed.

That said, there are a few articles on this and here is one description of a study supporting this surgery: https://www.obermair.info/latest-news/blog/breast-cancer-hysterectomy-and-removal-of-ovaries-and-tubes/ This is from 11 years ago and deals mostly with premenopausal women Here is another https://breastcancernow.org/about-breast-cancer/treatment/hormone-endocrine-therapy/ovarian-suppression-and-breast-cancer/ This discusses ovarian suppression and removal to help with breast cancer- again pre-menopause. The site breastcancer.org only discusses ovary removal in the context of BRCA.

I am wondering if this came up for you because you already have had a hysterectomy. This article says only women who have had both uterus and ovaries removed get this benefit for their breast cancer- again, mostly pre-menopause. I just can't ascertain if this is relevant to someone who has gone through menopause (and is BRCA negative) and would like to know what your oncologist thinks.

Post-menopause most of us have ovaries that aren't doing much so we take aromatase inhibitors to reduce estrogen produced by the adrenals below detectable levels. I have been told that after menopause only the adrenals and fat produce estrogen.

Have you asked you surgeon why they want to remove your ovaries? Can they share a study? What does your oncologist say? Would you get a second opinion?