As promised, my successful tapering off Effexor (Venlafaxine)

Posted by sheffieldsmith @sheffieldsmith, May 31, 2020

Below you will find the tapering plan that I used to successfully wean myself off Effexor (Venlafaxine). Feel free to share this with your doctor If you would like. I researched and came up with this plan, which was approved by my doctor, although she thought I could probably have weaned myself off sooner. But the reality is that we all have differing tolerance levels for tapering and weaning off this powerful drug from our bodies. Some people can taper faster, but usually not those who have been on this drug for years (like myself, since October 2002). I tapered off EffexorXR 150mg capsules about 5 years ago down to 75mg, and was on that maintenance dosage for a couple of years until I started weaning off the 75mg a year ago in April 2019. As of October, 2029, I’ve been withdrawal symptom free, but I still have occasional periods of anxiety when triggered. But I realize these waves of anxiety will soon pass, and I cope by deep breathing, taking a walk, having a cup of chamomile tea, etc. Cutting my exposure to watching upsetting news has really helped a lot as well. These days I seek things that bring joy and peace in such a turbulent world. Wishing you all a successful weaning off this powerful drug.

Weaning off Venlafaxine XR 75mg (Effexor-(extended release)capsules:
Weaning plan off plan that worked for BSS:
1. Inform your doctor you are tapering down from 75 mg Venlafaxine and ask them to prescribe 37.50 tabs to help with tapering doses (1/2 dosage down from 75 mg Venlafaxine capsules). The tabs are easier to cut into halves and quarter dosages than counting out beads from the capsules.
2. Begin your taper only after you are on a non-withdrawal symptomatic dosage level. If you were having w/d symptoms at 75 mg, you’ll need to go back to the level at which you were symptomless and stay there for 2-3 weeks before deceasing to a slow taper. NOTE: after successfully tapering from 150mg Venlafaxine down to 75mg for a month, I was unable to tolerate a drop cold turkey from a daily dosage of 75mg down to 37.50mg (50%) without having bothersome withdrawal symptoms of dizziness, brain fog, brain zaps, and nausea. So after researching various tapering plans, I came up with a slower tapering schedule my body could tolerate to finish the tapering from 75mg to 37.50mg, and then on to complete the tapering. Your body may even need slower tapering, so adjust according.
3. Week 1-2: Take 75mg caps MWFSu; take 37.50mg tab on alternate days Tu,Th, Sa. At the end of week 2, if you only have relatively mild to no withdrawal symptoms, proceed to week 3. IMPORTANT: If you have intolerable symptoms, adjust to a slower tapering schedule by adding an additional 1/2 tab on the alternate days (or take a total of one and a half 37.50 tabs on alternate days). You’ll then have to tweak the rest of your tapering schedule. If all goes well, proceed with week 3.
4. Week 3-4: Cut a few 37.50 tabs in half with a pill cutter or exacto knife blade to create quarter pieces. Take 37.50mg tab on MWFSu and take 3/4 tab on alternate days Tu, Th, Sa.
5. Week 5-6: Take 3/4 of a tab MWFSu, and take 1/2 tab on alternate days Tu, Th, Sa. If only mild symptoms, proceed to week 5.
6. Week 7-8: Take 1/2 tab on MWFSu; and take 1/4 tab on alternate days Tu, Th, Sa. If no symptoms, continue to week 7.
7. Week 9-10: Take 1/4 tab on MWFSu; and take 1/8 tab (cut 1/4 tabs in half) on alternate days Tu, Th, Sa. *Notice the quartering of doses into crumbs now...very important to keep small dosage tapering to remain withdrawal symptom free.
8. Week 11-12: Take 1/8 tab crumb on MWFSu; take none on alternate days Tu, Th, Sa. *If skipping alternate days produces symptoms, stay on 1/8 tab crumbs for a couple of weeks before alternating skip days for a couple of weeks.
You’ll find that this schedule may have to be tweaked for you by extending the time you stay on a taper...possibly up to 3-4 weeks before beginning a new tapering down. It all depends on how you tolerate the first two weeks.

Interested in more discussions like this? Go to the Depression & Anxiety Support Group.

@edmundmerrick

I am most worried about the possibility of a cessation of the importation of the drug's generic version, venefaxine and even name brand Effexor. I had a problem when one of my blood pressure medicines ceased production. Luckily there was a similar alternative and no withdrawal. If the drug, venafaxine, cannot be imported from China or India or wherever it is made, what happens then? What if it is not available? There will be a lot of suffering when we all have to go cold turkey. I am on 225 mgs and have been on it for more than 20 years. I am scared - very scared about this since the world is a powderkeg. I received no information and no warning from my psychiatrist about withdrawal and I think that is immoral and unprofessional. I know there are pluses to psychotropics but it was prescribed and is given to patients as if it were candy. This is my second day of lowering my dosage and I feel dizzy, angry and am dreading the future. If this is day two of withdrawal and I fear the future will get worse, I will have to go back to my original dosage. In addition, I had to fight my horrible Medicare Advantage Plan from Aetna as they sent me a letter that the drug plan is making it so I can only buy one pill each day even though I am taking three a day now. It seems that all I have done since I retired was to fight my insurance company because I have to depend on their Know nothing customer support people who all read prepared remarks from a script. What a foul system.

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Have you sufficiently researched how to lower the dosage? It is important to do it slowly and in small reductions. I filed a complaint with the FDA that this drug is not supplied in smaller amounts, so as to facilitate withdrawal. Unless they receive a barrage of complaints, however, the FDA will do nothing about it.
The UK now requires warnings about this drug; it's called informed consent. Sadly, it is not yet required in the United States.
I am sorry you have had a bad experience with a "Medicare Advantage" plan. After witnessing the nightmare my parents went through while enrolled in one, I never recommend it, if one can afford to stay in Medicare.
Please learn some tips and tricks to lessen your worries! You can find helpful hints on this website. My anxiety ballooned during withdrawal; I had to resume this drug (at a lower dose than I was on, thankfully), but learning coping techniques is invaluable. Good luck and best wishes to you.

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@looplu79

Thank you Just ordered book as suggested

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See if information here helps: https://iipdw.org

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Great to hear your experience!

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@edmundmerrick

I am most worried about the possibility of a cessation of the importation of the drug's generic version, venefaxine and even name brand Effexor. I had a problem when one of my blood pressure medicines ceased production. Luckily there was a similar alternative and no withdrawal. If the drug, venafaxine, cannot be imported from China or India or wherever it is made, what happens then? What if it is not available? There will be a lot of suffering when we all have to go cold turkey. I am on 225 mgs and have been on it for more than 20 years. I am scared - very scared about this since the world is a powderkeg. I received no information and no warning from my psychiatrist about withdrawal and I think that is immoral and unprofessional. I know there are pluses to psychotropics but it was prescribed and is given to patients as if it were candy. This is my second day of lowering my dosage and I feel dizzy, angry and am dreading the future. If this is day two of withdrawal and I fear the future will get worse, I will have to go back to my original dosage. In addition, I had to fight my horrible Medicare Advantage Plan from Aetna as they sent me a letter that the drug plan is making it so I can only buy one pill each day even though I am taking three a day now. It seems that all I have done since I retired was to fight my insurance company because I have to depend on their Know nothing customer support people who all read prepared remarks from a script. What a foul system.

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Not long ago I was taking Zoloft. Now I am taking Venlafaxine 75mg daily. I have a wonderful team of doctors at Virginia Mason Franciscan Health in Seattle. I give them the credit.

Namaste 🙏🏻

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@njoys

Have you sufficiently researched how to lower the dosage? It is important to do it slowly and in small reductions. I filed a complaint with the FDA that this drug is not supplied in smaller amounts, so as to facilitate withdrawal. Unless they receive a barrage of complaints, however, the FDA will do nothing about it.
The UK now requires warnings about this drug; it's called informed consent. Sadly, it is not yet required in the United States.
I am sorry you have had a bad experience with a "Medicare Advantage" plan. After witnessing the nightmare my parents went through while enrolled in one, I never recommend it, if one can afford to stay in Medicare.
Please learn some tips and tricks to lessen your worries! You can find helpful hints on this website. My anxiety ballooned during withdrawal; I had to resume this drug (at a lower dose than I was on, thankfully), but learning coping techniques is invaluable. Good luck and best wishes to you.

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Thank you for your comment. The United States should require that doctors that prescribe the pill should be required to discuss withdrawal. Of course, our government is awful in that regard. My wife and I got Lymphoma from using Roundup and are involved in a lawsuit involving the manufacturer who produced this product. It still is on the shelves throughout NY and in other states. It is banned throughout Europe. Our government protect Americans? Of course not.

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Hi! Do you know what mg you got down to in the end? Im so sorry if I missed that part. I had 37.5 capsules so was adjusting the amount of beads in the capsules and tapering that way. I got down to around 4.6 mg and I’m really hoping that’s enough to stop now!

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This is super helpful---do you have any suggestions for tapering while taking capsules? I'm weaning from 37.5mg capsules. thanks!

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@kosslertaylor

This is super helpful---do you have any suggestions for tapering while taking capsules? I'm weaning from 37.5mg capsules. thanks!

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My doctor asked the chemist to give liquid form so that tapering could be in small doses

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Hello, I'm new here.
I'm 68 and have been on venlafaxine 300 mg for about 4 years now.
I had been taking 450 mg since 1995.
I asked my doctor to help me come down even more last year and he prescribed a bottle of 75 mg.
I was too scared to do it back then but now I've decided that this is a time. So I have been taking 150 mg plus one 75 mg each day for five days now.
I'm also taking trazadone 200 mg and Lorazepam.
I'm here mostly for support but if anybody has any suggestions or comments, I'm open minded.
Thank you for reading.

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@littcann
Are you having withdrawal side effects? 450 down to 225 is a large taper. I would take it much much slower.
Jake

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