@sungal some are staying on Prolia 8-10 years apparently but for those of us in our 70's, that means into our 80's and then stopping and doing Reclast....When I am 80+ I would consider Prolia if it was tolerable and if the effect on immune system is okayed by research and MD's (I have lupus). I have a friend who is 83 and taking it for the rest of her life, apparently. She has not been told about a need to stop or rebound and follow-up and I did not enlighten her 🙂