← Return to Reclast Infusions: Side-effects & Recovery time

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@bluebonnet242

I had bookmarked this information from a previous post @gently made regarding reclast infusion. I didn’t copy the entire post, just the information pertinent to reclast infusion instructions.

From @gently
I have some advice from a doctor at Stanford about how to take Reclast to diminish side effects. He ran the clinical trials on Reclast. So this passage which I quote is meticulous. Don't let the complexity stir you against the drug. You might print the instructions and give them to the prescribing administering medical personnel, if you decide on Reclast. He also prefers Reclast after the full Forteo or Tymlos 18 months.
I won't take Evenity or Prolia. Although, if there were nothing else. . . I'm no so happy about the mechanism of action of the bisphosphonates. And am trying to figure a way without them.

"Have the infusion nurse dilute the 5mg in 100m LD5W into 500mLof NS so that the now 600mL infuses over 60 minutes.
Making the N-BP liss concentrated and infusing it more slowly substantially improves the renal safety based on data.
Administer 650mg of acetaminophen at the same time of the infusion and instruct the patient to take the same dose with dinner and at bedtime the day of the infusion, and with all three meals and at bedtime the day after the infusion, and a final dose with breakfast the 2nd morning after the infusion. This reduces the risk of a symptomatic acute phase reaction (APR) from about 22% to < 1%.
The 3rd thing I do is repeat the BTM (bone turnover markers) U, NTx and serum BSAP 4-6 weeks after the infusion to assess the maximal effect of bone turnover rate. This serves as a comparison when I repeat BTMs 12 months after the infusion. In my extensive 32 years of experience with IV bisphosphonates the average woman only needs a second infusion after an average of 24 months."

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Replies to "I had bookmarked this information from a previous post @gently made regarding reclast infusion. I didn’t..."

I feel very fortunate. I had my first Reclast infusion on May 9. I had a few aches the next day but nothing serious. No side effects that I'm aware of since then. I did ask the nurses for a longer infusion and they were fine with that. I asked for one hour. I drank considerable water the day before and day of. I did take one or two Tylenol. I am so sorry for those who did not have an easy time.