@sjwhit Welcome to Mayo Clinic Connect.

A low anion gap reading is indicative of the acid-base balance in your blood. It could be caused by low protein, a medication side effect, or electrolyte unbalance. Your doctor is probably looking at the complete lab report. When was the last time you had had a complete report? Did your doctor indicate a need for further testing?

You will read from many members, that Google can be a blessing or a nightmare. It's easy to find information that is not clear. It's easy to find information that is good. Diagnosing multiple myeloma is not a clearcut procedure, and one test result for anion gap is not necessarily cause for concern.

My suggestion is to contact your doctor or his nurse practitioner [doctors these days are so hard to pin down without an appointment!] and ask if there is cause for concern. Will you do that?
Ginger