NSCLC KRAS G12V Stage 2A treatment?

Hi @nsclckrasg12v, welcome to Connect! Has your oncologist recommended any continuing maintenance therapies; an inhibitor, or additional chemo? Future scans?

Hello, I had surgery and diagnosed at stage 2A with Kras mutation G12V. I had 2 rounds of chemo Pemetrexed and Cisplatin. I was supposed to get 4 rounds but they had to stop due to side effects. Now we are just going to follow up with chest CTs but I feel helpless and terrified after all the reading I’ve done that it always returns with this mutation even at early stage. The doctor said no other treatment at this point.

Hi there, there is a wonderful Facebook group called KRAS Kickers. It’s full of helpful info about clinical trials and scientific advances for this mutation. I have G12D. I have gained strength and hope from this amazing organization devoted to helping those with the KRAS Mutation. I highly recommend it. Sending you peaceful thoughts at this stressful time.

Thank you so much. I will check it out

What about Folfirinox? In Canada (where I am) it is the standard of care post resection. I was stage 2B. I had Whipple Feb.9, am having 12 rounds of Folfirinox, number 6 tomorrow. Also I was in an immunotherapy clinical trial prior to surgery, durvalumab and oleclumab.

Hi @dalegantous, From what I'm finding Folfirinox has been successful for pancreatic cancers, but I'm not seeing that it's been used for EGFR or other lung cancers. Sometimes drugs for one cancer are applicable to other cancers, if the drivers of the cancer are similar. Do you have experience with this drug in non-pancreatic cancers?

No sorry I wrote that post before I realized it was for a different cancer, apologies.

No problem at all! Just wanted to make sure we weren't missing anything.
Best of luck to you with your treatment! I hope it's wildly successful with minimal side effects. 🙂