Stopping Evenity Early

I went in for my second Evenity today and declined the second shot. The nurse said they have people stop early at 6 months, but not sooner.

Here is what I wrote elsewhere about today and my decision:

I had met with an allergist at the request of my endo. Allergist said I should pause between shots to ascertain effect before having second one. Nurse said I could only have a one minute pause. I got her to wait three. I decided against the second injection. Thigh injections are absorbed more slowly that tummy. By the time I got to my car, same burning band of tightness in mid abdomen, but more tolerable than two injections last month (which had an intense effect w/in a minute).

I read initial studies that based dose on weight. Standard dose is 3mg/kg for someone 150 lbs. I weigh 104. Essentially 3mg/kg would be about 140mg Evenity. One shot is 105mg, two shots is 210mg. Basically I got 2m/kg with one shot versus standard 3. That was reported as 1/3 less effective but still pretty good. Basically 10% increase vs 16% (see post above by @normahorn).

People are smart to stop at 6 mos! I asked about it but was told any muscle
And joint pain I had were not related and I wasn’t proactive enough to stop.

I would have done more honestly. But I already had excellent gains from Tymlos and Evenity was causing some unpleasant sensations. There is an argument to do 4-6 months (depending on P1NP) to get the bone building part of Evenity and there is a study seeing whether Reclast can be started then rather than at 12 months.

@windyshores can you tell us anything else about this study?

@sbcher what does this mean? Are you saying your bone density got worse on Evenity and that your DEXA was -2.5?

Yes. My bone density got worse using Evenity.

What were your starting DEXA and ending DEXA scores after Evenity?

@sbcher what does this mean? Are you saying your bone density got worse on Evenity and that your DEXA was -2.5?