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MCRC with peritoneal Mets. Is Immunotherapy an option?
Colorectal Cancer | Last Active: Jun 22, 2024 | Replies (11)Comment receiving replies
Hi - Panitumumab is immunotherapy.... It is an antibody that has been shown to be effective with BRAS CRC, however for MSS cancers, immunotherapy typically has been found not to be that effective and is not indicated. For this reason I suggest you change oncologists, and try to go to Memorial Sloan Kettering, MD Anderson or Mayo for a consult. You mentioned two rounds of chemo, what was the chemo regimen exactly how many courses did you have?
Replies to "Hi - Panitumumab is immunotherapy.... It is an antibody that has been shown to be effective..."
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Hello
Panitumumab is actually a monoclonal antibody and I am taking it with BRAFTOVI (Encorafenib) which is specific to the BRAF v600e mutation. They worked really well but I am becoming resistant to it. My mets in the peritoneum was not scannable (V small tumors) but (un)fortunately is now big enough to be seen. I am already being treated at MSK and have received CAPOX then Folfiri, avastin so far but will start the PIPAC trial at Northwell soon.
I have contacted Dr Morris at MD Anderson regarding his Clinical trial which I believe could be a game changer for MSS cancers like mine.
I'll post updates of my treatment so others with similar disease can maybe benefit from my experience.
Tim