What happens after Tymlos?

Posted by alknapp @alknapp, Feb 21 4:55pm

I’m going to be finishing the 18 month course of Tymlos in April/May of this year. Endo is saying that I should follow that with Prolia (within weeks) and then Reclast.

Has anyone else followed that treatment plan or have any comments about it?

Thank you.

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@gravity3

My situation is similar to yours. 76
Early menopause at 38. Spotty short duration hrt. I am having a functional medicine consult in August to see about testosterone and perhaps some form of estrogen. Would love to keep up with your discoveries. And kudos for having a doc who supports you.

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@gravity3 Hi there. My cardiologist is very confident with HRT replacement after finishing up my Tymlos. My rheumatologist wants me to begin Reclast infusion, so I’m researching and weighing my risks and benefits from both. I know I need HRT for my girlie parts for sure because I have suffered for years with vaginal atrophy so that will be a plus. But I would like the least amount of medication to maintain the gains I’ve had with Tymlos. I will have another Dexa scan next month and will see if the additional months on this med made a difference. I had a Dexa in Nov after being on Tymlos for 18 months but my doc approved for me to continue to the 24th month. Hoping there will be more gains.
I know it will take a couple of months for me to notice a difference with the HRT so I’m hoping I will feel the difference in my sleep, energy, sex, moods, etc. My doc says I will. Have a great weekend!

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@dooshie

@gravity3 Hi there. My cardiologist is very confident with HRT replacement after finishing up my Tymlos. My rheumatologist wants me to begin Reclast infusion, so I’m researching and weighing my risks and benefits from both. I know I need HRT for my girlie parts for sure because I have suffered for years with vaginal atrophy so that will be a plus. But I would like the least amount of medication to maintain the gains I’ve had with Tymlos. I will have another Dexa scan next month and will see if the additional months on this med made a difference. I had a Dexa in Nov after being on Tymlos for 18 months but my doc approved for me to continue to the 24th month. Hoping there will be more gains.
I know it will take a couple of months for me to notice a difference with the HRT so I’m hoping I will feel the difference in my sleep, energy, sex, moods, etc. My doc says I will. Have a great weekend!

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@dooshie just to be clear, while my Reclast dose will be lower, it will also be more frequent. Much depends on how I react (my first infusion is this week) and the doctor leaves the dose and timing up to me, as long as it meets his guidelines for effectiveness. He gives me parameters and I appreciate both his guidance and his caution. I have afib and kidney disease so the suggestion of lower dose came from the doctor.

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@windyshores

@dooshie just to be clear, while my Reclast dose will be lower, it will also be more frequent. Much depends on how I react (my first infusion is this week) and the doctor leaves the dose and timing up to me, as long as it meets his guidelines for effectiveness. He gives me parameters and I appreciate both his guidance and his caution. I have afib and kidney disease so the suggestion of lower dose came from the doctor.

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@windyshores thanks for the clarification on your Reclast infusion dosage. I personally would prefer not to continue osteo medication but I also don’t want to lose the gains I’ve made with Tymlos. I’m hoping to begin my HRT therapy this month and if an osteo med is necessary then decide on which one I will benefit from with minimal side effects. I’ve never fractured and pray that doesn’t happen once I’m off the Tymlos.

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@dooshie

@windyshores thanks for the clarification on your Reclast infusion dosage. I personally would prefer not to continue osteo medication but I also don’t want to lose the gains I’ve made with Tymlos. I’m hoping to begin my HRT therapy this month and if an osteo med is necessary then decide on which one I will benefit from with minimal side effects. I’ve never fractured and pray that doesn’t happen once I’m off the Tymlos.

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@dooshie does your doctor think that HRT is strong enough to maintain your gains? My image of Reclast is that it coats the bones and literally "locks in" the gains. Curious who advised HRT for you. I have not seen studies on this and would love to know more (not for me, I can't take hormones obviously).

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@windyshores my cardiologist is the one recommending the HRT, mainly because of my lack of hormones, not necessarily for my bones. He believes that they will protect my bones, however, to what extent he doesn’t know. I would love not to go back on osteo meds but I’d also hate to see my gains lost. Decisions, decisions, decision. Not always easy.

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@dooshie

@windyshores my cardiologist is the one recommending the HRT, mainly because of my lack of hormones, not necessarily for my bones. He believes that they will protect my bones, however, to what extent he doesn’t know. I would love not to go back on osteo meds but I’d also hate to see my gains lost. Decisions, decisions, decision. Not always easy.

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@dooshie it is so hard to keep track! I am glad that HRT will be helpful for you in your situation!

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@windyshores i hope that it does what I would like it to do, for all my health woes.

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@dooshie

@windyshores i hope that it does what I would like it to do, for all my health woes.

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Hope so too. It can't hurt. Let us know!

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@gravity3

What is his rational for wanting prolia? Is this an endocrinologist? If not, how about a second opinion?

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He claims it is the best drug on the market to hold the gains I made with Tymlos. He is a Rheumatologist who was highly recommended. Good idea about the 2nd opinion, tho.

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