@nbadry - my side effects are relatively mild: occasional joint pain, initially some itching, and fatigue. Round 1 I was on 10mg and the fatigue was worse. The dose also had a negative affect on my platelets and WBC. I had to wait many weeks for platelets and WBC to come back up so I could start the 5mg dose, which I will be on for some undefined period of time. I am feeling great now. All my values are normal right now. The first few months can be a challenge. For me the side effects were not debilitating.