My husband is on 28 of 38 planned treatments. He is also having a difficult time. His RO gave him a medrol dose pack which helped a bit and has now extended it with 5 additional days of dexamethasone. He also uses hyaluronic suppositories, Imodium and bentyl and literally a no fiber diet. He is on a 4 treatments per week schedule at this point. Hopefully this will allow him to complete but we may have to pause if he can’t tolerate it. Let us know what you hear about the effects of pausing on treatment outcome. I will keep you in my prayers. This is an awful illness.