hi @mayblin. I did two years of Tymlos and had a DEXA after 18 months. I am considering self-pay for a DEXA..next covered one is April 2025. My doctor doesn't do bone marker testing. As a result I have seen another doctor who does, and after several visits with McCormick (I have seen him for years) I had my PCP order them. But they have not been very useful and for now I have no need.
PINP was disappointing at 18 months with Tymlos (but I had no valid baseline since intended baseline was not fasting) and disappointing with Evenity (possibly I missed the peak but I doubt it).
It is a feeling of flying a plane in the dark with no instrument panel at times. I just watched a couple of videos- Paul Miller and a doctor with the IDF- and they say "we don't know" a lot. The whole field is full of "we don't know yets."
Noone has much to say about what to do after Reclast, besides a possible drug holiday followed by what?
My main concern now is being able to do an anabolic again after Reclast. I am going to ask about risendronate though my esophagus might not like it. I don't really trust my DEXA's after Tymlos. The gains were too large! And my femur neck was still -3.6. I might buy hip pads.
It may be possible to do another short burst (for me, others might do longer) Evenity after Reclast. Guess what? They don't know yet!
Hope you had a nice vacation. You were missed here!
@windyshores if you are considering repeating anabolic therapy in the future, I think a dexa right now will provide one piece of vital info, of the effect of short term 4mo evenity on you. Do it now before bmd affected by recent reclast infusion? My take
Repeating tymlos seems ideal since you responded to it magnificently, although the prospect for its extended usage isn't clear yet. Assuming the last 6 mo (19-24) of tymlos didn't have much of anabolic effect (don't know for sure, but for some ppl this is true, forteo more so than tymlos), your dexa scan at one year (now) from last one would reflect mostly evenity's effect. Knowing how you fare with evenity will give you a good base for future decision making.
Repeated use of anabolics after bisphosphonates especially prolonged exposure, is an untested field for sure since forteo's lifetime usage limit was lifted not that long ago. We sure can wish active studies are being conducted and many work get published soon. Meanwhile anecdotal counts and shared experiences on this forum will shed some lights.