@rjd I took Tymlos for two years and Evenity for 4 months. After either drug, I was told Reclast was necessary (I cannot take Fosamax due to GERD, and Reclast does a better job of coating the bones). The mechanism of "rebound" is not the same at all as with Prolia. In fact, though I have heard that term applied to all these situations, I would actually just say that without Reclast, I would lose my gains from the other two medications- I was told in two years. The term "rebound" is probably best used for Prolia discontinuation!

I honestly think that Evenity is too new for the doctors to really know, and more research needs to be done. Since it is anti-resoprtive, I have read they are looking into whether Evenity works without Reclast and also whether Evenity could be done for 6 months and Reclast could replace the last 6 months of Evenity. None of this is anywhere near clear yet>