CHIP (clonal hematopoiesis of indeterminate potential) is a type of excess blood cell production by the bone marrow caused by a genetic mutation in the DNA, either inherited or acquired later related to aging. It’s similar to MGUS ( monoclonal gammopathy of undetermined significance) which causes the M spike reflectinng abnormal proteins produced by plasma cells that form antibodies. MGUS is common and CHIP is a rather new kid on the block. The Dana Farber organization is doing a lot of research on CHIP and you can find a good article at blog.dana-farber.org on CHIP. I am guessing that having both is uncommon. Both conditions require monitoring of blood counts every 3-6 months and both are associated with increased inflammation. Both are precursors to blood cancers but at a very low incidence. Antiplatelet therapymay be warranted if the overproduction is of red cells, making the blood thicker and more likely to clot.
The good news is that no treatment is needed as long as blood counts remain stable.