This has to be a very difficult decision for you on whether to try again with the transplant or not for your little boy. I know personally how challenging it is to have a bone marrow transplant and can’t imagine trying to explain all of this to a child of three.

There are significant advances taking place in gene therapy which may offer other options in the future, but right now, a bone marrow/stem cell transplant remains the only potential cure for sickle cell anemia.

Did his doctor feel the donor cells didn’t engraft or was there a rejection of the cells? How did your little boy do the first time?

Hi @caizer, I just wanted to check in with you to see if you’ve learned anymore about your little boy’s condition and how’s he’s doing. Have you decided to try another transplant or have you been able to speak with his doctor about other potential options?