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Prolia and its side effects.

Osteoporosis & Bone Health | Last Active: Aug 20 10:39pm | Replies (69)

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@gently

The trouble with Prolia is the "resevoir" of preosteoclasts. You need the strongest medication to stop them. Zoledronate has the best mechanisms.
There is evidence that teriparatide therapy is more effective with Prolia. The HD Data trial evidenced that Prolia is able to "fully" inhibit the increased osteclast activity of Forteo It's possible to begin Tymlos or Forteo before the six months of Prolia is exhausted, You'd still need the antiosteoclast-antiresorptive at the end of six months. Would you want to stop the pth with the initiation of bisphosphonates. Maybe not.
I'm not happy with the idea of taking two of these pharmaceuticals concomitantly. Too many averse effects with just one.

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Replies to "The trouble with Prolia is the "resevoir" of preosteoclasts. You need the strongest medication to stop..."

Thank you everyone. This is so much info to swallow and digest but it is much appreciated ❤️