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Prolia and its side effects.

Osteoporosis & Bone Health | Last Active: 2 days ago | Replies (48)

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@windyshores

How many injections have you had? With fractures, it is usually recommended to do Forteo, Tymlos or Evenity.

The problem is that there is a rebound with Prolia when stopped, which usually requires Reclast or Fosamax to avoid. I have read and seen on videos that Tymlos and Forteo are not effective after Prolia but I do not know if that is true after, say, just one shot, or if it is true for a long time. It is also possible that Evenity would work, but you would have to find out if it stops any Prolia rebound that you might deal with. Evenity is quite potent in building bones.

What I mean by "rebound" :When Prolia is stopped, bone density goes down and fracture risk goes up unless that rebound is stopped with another drug. Basically the cells that break bone down, the osteoclasts, go dormant on Prolia and when the drug is stopped, they come roaring back- so to speak.

I hope you can find a really good endocrinologist to guide you in this situation. My first fracture was at T12 from a traumatic fall. If you fractured getting into bed, that is concerning. I later fractured from an unwise movement so it is true, fractures beget fractures, You qualified for an "anabolic" bone builder. Prolia is an anti-resorptive, not an anabolic,

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Replies to "How many injections have you had? With fractures, it is usually recommended to do Forteo, Tymlos..."

I just had my 3rd injection with this second go round. So I started back on it in June 2023.