I was diagnosed two years ago with PVCV but doctored for two years before that with the itching. All of a sudden the blood work and a bone biopsy confirmed PCV with Jack 2. I do notice shortness of breath at times. I was on Hydroxyurea for 6 months Until my platelets dropped. Right now I take one baby aspirin a day. I do have ear and headaches slight but constant and my oncologist. Hemotologist says it is from the PCV. I also find that keeping busy and exercise does make me feel a lot better. I have chosen to live with this disease, and not let this disease determine how I live. None of us ever know how long we have anyway, I research all the time and hopeful that maybe someday they have a cure. Hope you find some answers for you, make sure you ask tons of questions and keep yourself informed. Remember some people live 20 years or more with this disease .