Autoimmune diagnosing problem

@brie87144 @brie87144
As a non-physician, I shall give you my opinion, but keep in mind that my opinion might be completely worthless or DEVASTATINGLY DANGEROUS. My first impression upon reading about your symptoms is that you might have multiple sclerosis (MS), or perhaps some syndrome that is a differential diagnosis for MS, such as acute progressive multifocal leukoencephalitis or several other syndromes.
http://emedicine.medscape.com/article/1146199-differential “Multiple Sclerosis Differential Diagnoses”

From Wikipedia, “A person with MS can have almost any neurological symptom or sign, with autonomic, visual, motor, and sensory problems being the most common. The specific symptoms are determined by the locations of the lesions within the nervous system, and may include loss of sensitivity or changes in sensation such as tingling, pins and needles or numbness, muscle weakness, very pronounced reflexes, muscle spasms, or difficulty in moving; difficulties with coordination and balance (ataxia); problems with speech or swallowing, visual problems (nystagmus, optic neuritis or double vision), feeling tired, acute or chronic pain, and bladder and bowel difficulties, among others.”
https://en.wikipedia.org/wiki/Multiple_sclerosis#Signs_and_symptoms
https://en.wikipedia.org/wiki/Helminthic_therapy
If I thought I had MS, I might be crazy enough to try the following non-FDA-approved experimental therapy:
https://autoimmunetherapies.com/candidate_diseases_for_helminthic_therapy_or_worm_therapy/multiple-sclerosis_helminthic_therapy.html

I have been going to doctors for years, being treated for Hasimotes disease. Everything was cool until the last few years. I am being plagued by fatigue, joint aches lesions in the mouth and tinnunitis. I have been to two rheumatologist, both said I have and autoimmune disorder, but don't know what. I am currently on Plaquenil for the last month with no relief. My question is how long does it take to get a diagnosis.

Don't give up. There is always a little bit more that can be checked, a fresh set of eyes could make the difference. Have you had an expert work up by a rheumatologist/immunologist? Have the basic autoimmune markers like ANA been checked and inflammation or lack of it noted? I can't pretend that I would catch anything that all of these experts have missed. I've heard of strange syndromes following an infection like:
http://www.ninds.nih.gov/disorders/gbs/detail_gbs.htm
but there are less obscure things that can cause strange overlapping symptoms, like Lyme Disease.

If you haven't seen an rheumatologist/immunologist put that next on your list. If you have, you might want him/her to check for more antibodies. I was very sick for several years and kept going to the doctor and complaining about it. They ran lots of blood work and found nothing other than mild anemia and that I carried HLA-B27. I started having episodes of freezing, shaking and weakness lasting several hours. Eventually I collapsed in the waiting room and when I was admitted into the hospital they ran some tests and told me that I had Grave's disease and was experiencing thyroid storm. Not a parallel with you but the point is that I bugged them for several years and it turns out they never ran thyroid tests until I almost dropped dead. Even good doctors can have a blind spot so you have to be a squeaky wheel, unpleasant s it may be. Hang in there.

Don't give up. There is always a little bit more that can be checked, a fresh set of eyes could make the difference. Have you had an expert work up by a rheumatologist/immunologist? Have the basic autoimmune markers like ANA been checked and inflammation or lack of it noted? I can't pretend that I would catch anything that all of these experts have missed. I've heard of strange syndromes following an infection like:
http://www.ninds.nih.gov/disorders/gbs/detail_gbs.htm
but there are less obscure things that can cause strange overlapping symptoms, like Lyme Disease.

If you haven't seen an rheumatologist/immunologist put that next on your list. If you have, you might want him/her to check for more antibodies. I was very sick for several years and kept going to the doctor and complaining about it. They ran lots of blood work and found nothing other than mild anemia and that I carried HLA-B27. I started having episodes of freezing, shaking and weakness lasting several hours. Eventually I collapsed in the waiting room and when I was admitted into the hospital they ran some tests and told me that I had Grave's disease and was experiencing thyroid storm. Not a parallel with you but the point is that I bugged them for several years and it turns out they never ran thyroid tests until I almost dropped dead. Even good doctors can have a blind spot so you have to be a squeaky wheel, unpleasant s it may be. Hang in there.

I have been going to doctors for years, being treated for Hasimotes disease. Everything was cool until the last few years. I am being plagued by fatigue, joint aches lesions in the mouth and tinnunitis. I have been to two rheumatologist, both said I have and autoimmune disorder, but don't know what. I am currently on Plaquenil for the last month with no relief. My question is how long does it take to get a diagnosis.

Don't give up. There is always a little bit more that can be checked, a fresh set of eyes could make the difference. Have you had an expert work up by a rheumatologist/immunologist? Have the basic autoimmune markers like ANA been checked and inflammation or lack of it noted? I can't pretend that I would catch anything that all of these experts have missed. I've heard of strange syndromes following an infection like:
http://www.ninds.nih.gov/disorders/gbs/detail_gbs.htm
but there are less obscure things that can cause strange overlapping symptoms, like Lyme Disease.

If you haven't seen an rheumatologist/immunologist put that next on your list. If you have, you might want him/her to check for more antibodies. I was very sick for several years and kept going to the doctor and complaining about it. They ran lots of blood work and found nothing other than mild anemia and that I carried HLA-B27. I started having episodes of freezing, shaking and weakness lasting several hours. Eventually I collapsed in the waiting room and when I was admitted into the hospital they ran some tests and told me that I had Grave's disease and was experiencing thyroid storm. Not a parallel with you but the point is that I bugged them for several years and it turns out they never ran thyroid tests until I almost dropped dead. Even good doctors can have a blind spot so you have to be a squeaky wheel, unpleasant s it may be. Hang in there.

Brie87144, I hope you are still on line, and curious. I have been thinking about your issues, and I have something to add. Please visit http://www.aarda.org for a list of autoimmune diseases. Why? I think I see in your list of tests no mention of kidney failure or issues. I say this because my kidneys do not wash out all the broken or mis-folded proteins from my plasma and serum. Then those proteins die in a couple hours and deposit themselves in any tissues, including nerves, muscles, bones, etc. They get in between cells in nerves and cause broken links in control nerves and sensory nerves. This cause paralysis, de-sensitization, shorted signals going from the brain to the tissues such as heart, stomach, muscles, etc. My simple suggestion is to have your doctor do a SERUM Free Light Chain@ assay, and send it to ARUP, Stanford, Mayo, Quant, Mass Gen, Sloan-Kettering, etc. Also do a 24-hour urine collection/protein search. If either of these proves positive, move up the scale on the tests. One of these top lobs can guide your process. I only know this much because I am going through the dX process with amyloidosis now, and am finally getting close to the truth. The diagnosis timeline in this area can last up to a half century. I started asking for help in about 1980. The disease is just now getting to the stage where dx is possible, although it will actually be more of a prognosis than a dx. So keep pushing your doctors. Educate yourself and your docs.