10 mg dose nightly. My rheumatologist and I had a conversation about precisely what you state regarding that it can quit working. But I have no alternatives. Cannot and will not take Humira, Cymbalta, or any other such as those due to serious sensitivity to majority of drugs. I'm talking scary hallucinations, night terrors and nightmares, as well as a host of other horrid symptoms. Initially had been prescribed amitriptyline also, and that drug I had to taper the doses until I was finally able to just eliminate it. It had contributed very unfavorable side effects, especially since it is actually prescribed as an antidepressant and I was on another antidepressant that wasn't addressing my depression (I got help for tapering and getting off that also!) and the ami just exacerbated what the Effexor XR was doing to me (and yes I finally got guidance and eliminated that drug also!). But the cyclo helps with muscle pain as well as makes me sleepy so I take 10 mg only at night, never during the day or I'd spend my time sleeping and then being angry at having had my day wasted! Despite the cyclo, I still experience periods of pain, and since I also have polymalgia rheumatica, that disorder knocks the fibromyalgia right out of the park. The PMR pain is totally different and even more intense than the fibromyalgia. My life has been and continues to be complicated. For me, a good day is measured by having an overall Pain Level score of 5 (pretty bearable in my book) or at times even less.

To further address your point: Yes, within medical journals, etc., that I researched, I did learn that most doctors prescribe the cyclo for a period of weeks and then stop for a few months, to then start the cycle again. I've never even asked about that nor would consider it. It's advisable to keep in mind that cyclobenzeprine IS a muscle relaxant so great caution must be taken to not take more than what is prescribed. As one doctor told me, it can indeed affect the heart since it IS a muscle!

I hope you can find your ways of dealing with the pain(s) of fibromyalgia. When I was first diagnosed, I told the doctor "I can't accept that diagnosis since it does not have a cure, and I have three young children to raise." So for a few years I did not seek medical help and took no meds, just ached horribly, had such non restorative sleep, and lived daily with ever-present pain. I finally faced the facts and accepted guidance and medication. I'll continue taking the cyclo in addition to a few priority prescribed drugs for my other health issues.

I wishy you well.💖