Evenity and side effects: What helps joint and muscle pain?

I had burning and tingling on Evenity but my calcium tested fine!

After my first set of Evenity injections in January, I started posting monthly about the side-effects I had experienced. They've been so minor that I stopped commenting after the third. I had exhaustion that started about a week after that one, then everything returned to normal.

Because people are more likely to share negative experiences than positive ones, I feel like it could be reassuring to continue my updates even when everything's going well. I'll bring things up-to-date.

My fourth set of injections was in April. The technique that the nurse used was different. She injected slowly. It was more painful than I experienced with the previous three, and that day the injection sites were very tender. I even had a burning sensation under the skin. It was more annoying than it was painful. I was trying to do focused work and it was distracting me.

I had my fifth set done by a different nurse last week. She's a no-nonsense, just get it done kind of person, so she did it fast. Afterward there wasn't much tenderness, and no burning at all though one injection site bruised.

An interesting thing that may, or may not be related, is a new occasional tingling nerve sensation (not really painful) in my ankles. Has anyone else had that anywhere on their body?

Yes! I have had two sets of injections and after my last one I started getting random tingly feelings in my lower jaw and around my ear. I know my provider will say it’s not related because she already told me that Evinity has no side effects (such as muscle pain, exhaustion, or neck. Anyone else had these electric sensations?

Yes! I have had two sets of injections and after my last one I started getting random tingly feelings in my lower jaw and around my ear. I know my provider will say it’s not related because she already told me that Evinity has no side effects (such as muscle pain, exhaustion, or neck. Anyone else had these electric sensations?

"ONJ associated with use of drugs such as bisphosphonates, denosumab, or romosozumab is referred to as “medication-related ONJ” or MRONJ.Apr 11, 2023" accordind to the American Dental Association.
It is rare! But with jaw pain more intense than ever before you might consider ( with your doctor) discontinuing Evenity. With the third injection you have received the best of the drug since the next 9 months would be antiresorptive. Paul Miller suggests that administering Evenity for three months might be a better option, since it was unknown at the time of approval that the next nine would be antiresporptive.
I would be wise to inform your prescribing physician (at the risk of being reassured that it could't be MRONJ), so you can begin considering what you might transition to.
There is currently no method of diagnosing ONJ. It begins with swelling and pain.
It could just be the joint pain that many experience with Evenity. I hope it goes away.

After my first set of Evenity injections in January, I started posting monthly about the side-effects I had experienced. They've been so minor that I stopped commenting after the third. I had exhaustion that started about a week after that one, then everything returned to normal.

Because people are more likely to share negative experiences than positive ones, I feel like it could be reassuring to continue my updates even when everything's going well. I'll bring things up-to-date.

My fourth set of injections was in April. The technique that the nurse used was different. She injected slowly. It was more painful than I experienced with the previous three, and that day the injection sites were very tender. I even had a burning sensation under the skin. It was more annoying than it was painful. I was trying to do focused work and it was distracting me.

I had my fifth set done by a different nurse last week. She's a no-nonsense, just get it done kind of person, so she did it fast. Afterward there wasn't much tenderness, and no burning at all though one injection site bruised.

An interesting thing that may, or may not be related, is a new occasional tingling nerve sensation (not really painful) in my ankles. Has anyone else had that anywhere on their body?

hopefullibrarian, quite helpful and thoughtful.
Because low blood calcium can cause tingling and pain in the hands or feet, Because Evenity can cause low blood calcium, you might want serum labs. Easier still to add calcium. I'd want to know, (and would have a foot x-ray) but would probably want to get rid of the pain right away. I hope it is just calcium.
"Evenity may also cause muscle spasms, neck pain, and burning or tingling (usually in the hands and feet)." https://www.healthline.com/health/drugs/evenity-side-effects--not my favorite source.