This is difficult, I went through the same thing with my wife. Our four children were helpful and supportive as she was thoroughly evaluated and eventually diagnosed, "Alzheimer's dementia with paranoid ideation". She was impossibly hostile with all that hostility directed at me, convinced that I had orchestrated a conspiracy against her. We even tried marriage counseling but after a few visits she refused to go, thinking the counselor was on my side. The gerontologist eventually achieved a reduction in this hostility through a combination of anti depressants and anti psychotics. The disease has advanced but with 24/7 caregiving on my part, we get through the days without much conflict. I read books and went to seminars on dementia to learn as much as possible and caregiver support groups at the Senior Center were helpful too. Many challenges and sometimes family drifts away being upset watching the personality changes. Prayers for you and your husband, you will have surprises, some good, some not so good. Keep in touch with this group, it's a great blessing.